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Posted at Oct 16, 2013 by JG

Analysis of age-related changes in the functional morphologies of salivary glands in mice » aobjournal.com

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Body and gland weights increased with age. Gland weight was significantly higher in group B than in groups A and C. Salivary lag time was significantly greater in group C than in groups A and B, and salivary flow rate was significantly greater in group B than in groups A and C. Histologic evaluations exhibited acinar cell atrophy, cytoplasmic vacuolization, lymphocyte infiltration, small mucin component and more periductal fibrosis in salivary glands of group C. TUNEL assays revealed that apoptotic salivary epithelial cells were significantly more numerous in group C than in groups A and B. 99mTc-pertechnetate excretion rate was significantly lower in group C than in groups A and B in SPECT.

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http://www.aobjournal.com/a...813%2900260-4/abstract?rss=yes

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