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Posted at Aug 23, 2012 by JG

Efficacy of the stannous ion and a biopolymer in toothpastes on enamel erosion/abrasion » sciencedirect.com

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Loss values (μm) for erosion only and placebo were 14.4 ± 4.5 and 20.2 ± 3.8, respectively, and 4.6 ± 1.9 for the positive control (p≤0.001 each compared to erosion only). The other loss values were: NaF/1 16.5 ± 3.0, NaF/2 14.0 ± 2.7, NaF/3 12.6 ± 3.9, NaF/SnCl2 14.7 ± 5.1, AmF/SnF2 13.5 ± 4.8, AmF/NaF/SnCl2 12.4 ± 4.2, AmF/NaF/SnCl2 + chitosan 6.6 ± 3.5 (except NaF/1 all p≤0.01 compared to placebo). AmF/NaF/SnCl2/chitosan was more effective than all other toothpastes (p≤0.01 each). Sn on the enamel surface ranged between 1.3 ± 0.3 and 2.8 ± 0.04 wt% with no obvious relationship with efficacy. The NaF and Sn2+ toothpastes without chitosan exhibited similar anti-erosion and abrasion-prevention effects. The experimental Sn2+ formulation with chitosan revealed promising results similar to those of the positive control.

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http://www.sciencedirect.co.../article/pii/S0300571212002230

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